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KMID : 1123920060200010171
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Korean Journal of Oriental Physiology and Pathology
2006 Volume.20 No. 1 p.171 ~ p.173
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Trichomonicidal Activity of Herbal Extracts Used in Traditional Medicine in Korea
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Kim Youn-Chul
Ryu Jae-Sook
Kim Hyoung-Jun
Choi Kyung-Min
Kim Hye-Sook
Park Hyun
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Abstract
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Trichomonicidal activity of thirty methanolic herbal extracts used in traditional medicine in Korea was evaluated. Trichomonas vaginalis was used as experimental model, and anti-Trichomonas activity was determined over cultures of the parasite in TYM Diamond medium. Six methanolic extracts such as Acanthopanacis Cortex, Agrimoniae Herba, Pulsatillae Radix, Sanguisorbae Radix, Sophorae Radix, and Torilidis Fructus showed more than 50% trichomonicidal activity at the concentration of 200 g/ml. These extracts were further fractionated into n-butanol soluble and aqueous phases. Except for Acanthopanacis Cortex, all of n-butanol soluble phases showed potent trichomonicidal activity, while none of aqueous phases exhibited trichomonicidal activity.
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KEYWORD
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Trichomonas vaginalis, Anti-Trichomonas, Korean traditional medicine
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